snake venom to heal wounds faster as IIT jodhpur developed antimicrobial peptide
Surjit Ghosh, professor in the Department of Bioscience and Bioengineering and Department of Smart Healthcare at IIT Jodhpur, said that the harmful elements in snake venom have been removed and only its antimicrobial properties have been used. According to NDTV, scientists have added a small helical peptide to its N-terminus so that the compound can easily enter the pathogen and kill it. It is noteworthy that due to the increasing use of antibiotics, there is a danger of drug resistance in bacteria and other germs. Scientists in the medical field are worried about this, because medicines will stop being effective, and diseases will become difficult to treat.
The antimicrobial peptide present in snake venom has different hydrophobicity and charge structure, due to which it becomes a powerful weapon to eliminate bacteria. Their capacity is said to be very high but it can be used for humans only to a limited extent. With this research, two things will now be solved very easily. The first is that it has the ability to form a membrane, due to which bacteria will not be able to develop resistance against it. Secondly, it can be used as a substance to remove infection. It will be effective on its own and can also be used by mixing it with other medicines.
The research has been done by Dr. Surjit Ghosh and his colleagues, Professor Dr. Samya Sen, Ramkamal Samat, Dr. Moumita Jash, Satyajit Ghosh, Rajshekhar Roy, Nabanita Mukherjee, Surojit Ghosh and Dr. Jayita Sarkar. It has been published in the Journal of Medicinal Chemistry.
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